Project Details

Integration of MARS and GWS modules in the ISMU Pipeline for facilitating molecular breeding for complex traits

Duration: 01/Nov/2011 - 31/Oct/2013

Locations: India,Asia

Project contact: Varshney, R, Rathore, A

Donor: Generation Challenge Program (GCP)/CIMMYT-Mexico

Marker-assisted backcrossing (MABC) is the most commonly used approach for molecular breeding in several crop species. However, this approach has bottlenecks for breeding for complex traits, such as drought tolerance, especially when the trait is controlled by many small effect QTLs and pyramiding of such a large number of QTLs through MABC often requires unmanageable population size. In such cases, recently two modern breeding approaches namely marker-assisted recurrent selection (MARS) and genome wide Selection (GWS) have gained momentum in crop breeding. While MARS deals with accumulation of large number of QTLs, GWS approach accumulates superior allele throughout the genome based on analysis of genome-wide marker profiling data and historical phenotyping data on a training population. Majority of times, these approaches involve the use of high-throughput (HTP) marker (mainly SNP) genotyping data or genotyping by sequencing (GBS) data. This project plans to identify the most appropriate MARS and GWS modules currently available by organizing an international workshop and integrating those tools in the ISMU pipeline in collaboration with experts in the area of MARS and GWS

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